Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Neurokinin 1 Receptor aa 350 to the C-terminus. The exact sequence is proprietary. Database link: P25103
K562, Jurkat and THP-1 cell lysates.
This product is a recombinant rabbit monoclonal antibody.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/70.
1/10000 - 1/50000. Detects a band of approximately 48 kDa (predicted molecular weight: 46 kDa).
This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
Belongs to the G-protein coupled receptor 1 family.