Overview

  • Product name
    Anti-Neurotensin Receptor 1 antibody
    See all Neurotensin Receptor 1 primary antibodies
  • Description
    Rabbit polyclonal to Neurotensin Receptor 1
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide conjugated to KLH, from an internal region of Human Neurotensin Receptor 1 (CAA49675.1).

  • Positive control
    • Human pancreas tissue; MCF7 cell extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab117592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 46 kDa.
ELISA 1/1000.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Relevance
    Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. NTR1 has been reported in brain, pancreas, and small intestine. ESTs have been isolated from brain and colon libraries.
  • Cellular localization
    Cell Membrane, Endoplasmic reticulum, Golgi Apparatus and Plasma membrane. Integral membrane protein.
  • Database links
  • Alternative names
    • High affinity levocabastine insensitive neurotensin receptor antibody
    • Neurotensin receptor 1 (high affinity) antibody
    • Neurotensin receptor type 1 antibody
    • NT R 1 antibody
    • NTR antibody
    • NTR1 antibody
    • NTR1_HUMAN antibody
    • NTRH antibody
    • NTRR antibody
    • NTSR 1 antibody
    see all

Images

  • ab117592, at 5 µg/ml, staining Neurotensin Receptor 1 in Formalin-fixed, Paraffin-embedded Human Pancreas tissue by Immunohistochemistry.
  • All lanes : Anti-Neurotensin Receptor 1 antibody (ab117592) at 1/500 dilution

    Lane 1 : MCF7 cell extract
    Lane 2 : MCF7 cell extract with immunizing peptide


    Predicted band size : 46 kDa

References

This product has been referenced in:
  • Kim JT  et al. Differential expression and tumorigenic function of neurotensin receptor 1 in neuroendocrine tumor cells. Oncotarget 6:26960-70 (2015). IHC . Read more (PubMed: 26298774) »
  • Ouyang Q  et al. Neurotensin promotes the progression of malignant glioma through NTSR1 and impacts the prognosis of glioma patients. Mol Cancer 14:21 (2015). Read more (PubMed: 25644759) »

See all 3 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab117592.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up