Anti-Neurotensin Receptor 1 antibody (ab66216)

Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab66216 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000. Detects a band of approximately 47 kDa (predicted molecular weight: 47 kDa).
IHC-Fr 1/1000.
ICC/IF 1/1000.

Target

  • RelevanceNeurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. NTR1 has been reported in brain, pancreas, and small intestine. ESTs have been isolated from brain and colon libraries.
  • Cellular localizationCell Membrane, Endoplasmic reticulum, Golgi Apparatus and Plasma membrane. Integral membrane protein.
  • Database links
  • Alternative names
    • High affinity levocabastine insensitive neurotensin receptor antibody
    • Neurotensin receptor 1 (high affinity) antibody
    • Neurotensin receptor type 1 antibody
    • NT R 1 antibody
    • NTR antibody
    • NTR1 antibody
    • NTR1_HUMAN antibody
    • NTRH antibody
    • NTRR antibody
    • NTSR 1 antibody
    see all

Anti-Neurotensin Receptor 1 antibody images

  • Top image: Light microscopic analysis of NTSR1 expression in primary afferent neurons (arrows) using 1:1000 ab66216 of PFA fixed cells.
    Bottom image: At higher magnification, neurons exhibit a cytoplasmic pattern of immunoreactivity (arrowheads).
  • All lanes : Anti-Neurotensin Receptor 1 antibody (ab66216) at 1/5000 dilution

    Lane 1 : DRG's
    Lane 2 : Lumbar spinal chord
    Lane 3 : brain

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 47 kDa
    Observed band size : 47 kDa

References for Anti-Neurotensin Receptor 1 antibody (ab66216)

ab66216 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"