Overview

  • Product name
    Anti-Neurotrophin 4 antibody
    See all Neurotrophin 4 primary antibodies
  • Description
    Rabbit polyclonal to Neurotrophin 4
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 35-84 (

    LAPEWDLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSE

    ) of Human Neurotrophin 4 (NP_006170).

  • Positive control
    • HT1080 cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab98347 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 22 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Target-derived survival factor for peripheral sensory sympathetic neurons.
  • Tissue specificity
    Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.
  • Involvement in disease
    Defects in NTF4 may be associated with susceptibility to primary open angle glaucoma type 1O (GLC1O) [MIM:613100]. A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place.
  • Sequence similarities
    Belongs to the NGF-beta family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • GLC10 antibody
    • GLC1O antibody
    • Neurotrophic factor 4 antibody
    • Neurotrophic factor 5 antibody
    • Neurotrophin 4 antibody
    • Neurotrophin 4/5 antibody
    • Neurotrophin 5 (neurotrophin 4/5) antibody
    • Neurotrophin 5 antibody
    • Neurotrophin-4 antibody
    • Neurotrophin-5 antibody
    • Neutrophic factor 4 antibody
    • Neutrophic factor 5 antibody
    • NT 4 antibody
    • NT 4/5 antibody
    • NT 5 antibody
    • NT-4 antibody
    • NT-5 antibody
    • NT4 antibody
    • NT4/5 antibody
    • NT4P antibody
    • NT5 antibody
    • NTF4 antibody
    • NTF4_HUMAN antibody
    • NTF5 antibody
    see all

Images

  • Anti-Neurotrophin 4 antibody (ab98347) at 1 µg/ml (in 5% skim milk / PBS buffer) + HT1080 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 22 kDa

References

ab98347 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab98347.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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