Anti-Neurotrophin 4 antibody - BSA and Azide free (ab24492)

Overview

  • Product name
    Anti-Neurotrophin 4 antibody - BSA and Azide free
    See all Neurotrophin 4 primary antibodies
  • Description
    Sheep polyclonal to Neurotrophin 4 - BSA and Azide free
  • Specificity
    Less than 1% cross reactivity against NGF, BDNF and NT3 by dot blot.
  • Tested applications
    Suitable for: ICC/IF, WB, ELISA, Inhibition Assaymore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human, Monkey
  • Immunogen

    Recombinant full length protein (Human)

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Purity
    Whole antiserum
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab24492 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent dilution.
WB 1/500 - 1/2000. Predicted molecular weight: 22 kDa.
ELISA 1/500 - 1/2000.
Inhibition Assay 1/10 - 1/50.

Target

  • Function
    Target-derived survival factor for peripheral sensory sympathetic neurons.
  • Tissue specificity
    Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.
  • Involvement in disease
    Defects in NTF4 may be associated with susceptibility to primary open angle glaucoma type 1O (GLC1O) [MIM:613100]. A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place.
  • Sequence similarities
    Belongs to the NGF-beta family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • GLC10 antibody
    • GLC1O antibody
    • Neurotrophic factor 4 antibody
    • Neurotrophic factor 5 antibody
    • Neurotrophin 4 antibody
    • Neurotrophin 4/5 antibody
    • Neurotrophin 5 (neurotrophin 4/5) antibody
    • Neurotrophin 5 antibody
    • Neurotrophin-4 antibody
    • Neurotrophin-5 antibody
    • Neutrophic factor 4 antibody
    • Neutrophic factor 5 antibody
    • NT 4 antibody
    • NT 4/5 antibody
    • NT 5 antibody
    • NT-4 antibody
    • NT-5 antibody
    • NT4 antibody
    • NT4/5 antibody
    • NT4P antibody
    • NT5 antibody
    • NTF4 antibody
    • NTF4_HUMAN antibody
    • NTF5 antibody
    see all

References

ab24492 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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