Anti-Neurotrophin 4 antibody - BSA and Azide free (ab24492)

Overview

  • Product nameAnti-Neurotrophin 4 antibody - BSA and Azide free
    See all Neurotrophin 4 primary antibodies
  • Description
    Sheep polyclonal to Neurotrophin 4 - BSA and Azide free
  • SpecificityLess than 1% cross reactivity against NGF, BDNF and NT3 by dot blot.
  • Tested applicationsSuitable for: ICC/IF, WB, ELISA, Inhibition Assaymore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human, Monkey
  • Immunogen

    Recombinant full length protein (Human)

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • PurityWhole antiserum
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab24492 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent dilution.
WB 1/500 - 1/2000. Predicted molecular weight: 22 kDa.
ELISA 1/500 - 1/2000.
Inhibition Assay 1/10 - 1/50.

Target

  • FunctionTarget-derived survival factor for peripheral sensory sympathetic neurons.
  • Tissue specificityHighest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.
  • Involvement in diseaseDefects in NTF4 may be associated with susceptibility to primary open angle glaucoma type 1O (GLC1O) [MIM:613100]. A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place.
  • Sequence similaritiesBelongs to the NGF-beta family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • GLC10 antibody
    • GLC1O antibody
    • Neurotrophic factor 4 antibody
    • Neurotrophic factor 5 antibody
    • Neurotrophin 4/5 antibody
    • Neurotrophin 5 (neurotrophin 4/5) antibody
    • Neurotrophin 5 antibody
    • Neurotrophin-4 antibody
    • Neurotrophin-5 antibody
    • Neutrophic factor 4 antibody
    • Neutrophic factor 5 antibody
    • NT 4 antibody
    • NT 4/5 antibody
    • NT 5 antibody
    • NT-4 antibody
    • NT-5 antibody
    • NT4 antibody
    • NT4/5 antibody
    • NT4P antibody
    • NT5 antibody
    • NTF4 antibody
    • NTF4_HUMAN antibody
    • NTF5 antibody
    see all

References for Anti-Neurotrophin 4 antibody - BSA and Azide free (ab24492)

ab24492 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"