Overview

  • Product nameAnti-Neurturin antibody
    See all Neurturin primary antibodies
  • Description
    Rabbit polyclonal to Neurturin
  • Tested applicationsSuitable for: ELISA, IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant full length protein (Human)

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: None
    Constituents: Whole serum
  • PurityWhole antiserum
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab49203 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
IHC-P
IHC-Fr
  • Application notes1 site ELISA: 1/5000.
    IHC-Fr: 1/2000.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionSupports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
    • Involvement in diseaseDefects in NRTN are a cause of Hirschsprung disease (HSCR) [MIM:142623]. In association with mutations of RET gene, and possibly with other loci, defects in NRTN are involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.
    • Sequence similaritiesBelongs to the TGF-beta family. GDNF subfamily.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • Neurturin antibody
      • Neurturin precursor antibody
      • NRTN antibody
      • NRTN_HUMAN antibody
      • NTN antibody
      • prepro-neurturin antibody
      see all

    Anti-Neurturin antibody images

    • ab49203 staining Neurturin in Human cochleae tissue sections by Immunohistochemistry. Samples were incubated with primary antibody (1/100) for 20 hours at 4°C. Positive Neuturin immunostaining was found in the spiral ganglion cell bodies and nerve fibers. The circle indicates peripheral nerve processes, arrows point to the nerve bundles of the central processes. 

    References for Anti-Neurturin antibody (ab49203)

    This product has been referenced in:
    • Liu W & Rask-Andersen H Immunohistological analysis of neurturin and its receptors in human cochlea. Auris Nasus Larynx N/A:N/A (2013). IHC-P, IHC-Fr ; Human . Read more (PubMed: 24139947) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab49203.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"