Overview

  • Product name
  • Description
    Sheep polyclonal to Neurturin
  • Specificity
    Cross reactivity: This antibody is known to react with human, mouse, rat and other rodents. Cross reactivity with other species has not been tested. No cross reactivity with Glial cell line-derived Neurotrophic Factor
  • Tested applications
    Suitable for: Dot blot, ELISA, IHC-Fr, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein (Human).

  • General notes
    This antibody has been used for immunohistochemistry and immunoblotting.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Purity
    Whole antiserum
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab6208 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Dot blot
ELISA
IHC-Fr
WB
  • Application notes
    Immunohistochemistry: 1/2,000-3,000
    Western Blot: 1/3,000
    Immunoblot: 1/3,000
    1 site ELISA: 1/2,000-3,000
    Biological Inhibition: Not tested.
  • Target

    • Function
      Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
    • Involvement in disease
      Defects in NRTN are a cause of Hirschsprung disease (HSCR) [MIM:142623]. In association with mutations of RET gene, and possibly with other loci, defects in NRTN are involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.
    • Sequence similarities
      Belongs to the TGF-beta family. GDNF subfamily.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • Neurturin antibody
      • Neurturin precursor antibody
      • NRTN antibody
      • NRTN_HUMAN antibody
      • NTN antibody
      • prepro-neurturin antibody
      see all

    References for Anti-Neurturin antibody (ab6208)

    ab6208 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. Ab6208 has been tested for application in Western blot, ELISA, Immunohistochemistry (Frozen sections), and Dot Blot. We unfortunately do not have any images for this antibody available at this time. As ab6208 was raised in a...

    Read More

    We supply a Neurturin peptide (ab8393) and a human Neurturin recombinant protein (ab9840). Please see the website for further information on each of these products.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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