• Product nameAnti-Neurturin antibody
    See all Neurturin primary antibodies
  • Description
    Rabbit polyclonal to Neurturin
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to amino acids 178-193 of Human Neurturin (Peptide available as ab8393.)


  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPBS with 0.02% sodium azide
  • Concentration information loading...
  • PurityIgG fraction
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab8061 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Detects a band of approximately 14 kDa.Can be blocked with Neurturin peptide (ab8393).
IHC-P Use a concentration of 5 µg/ml.


  • FunctionSupports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
  • Involvement in diseaseDefects in NRTN are a cause of Hirschsprung disease (HSCR) [MIM:142623]. In association with mutations of RET gene, and possibly with other loci, defects in NRTN are involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.
  • Sequence similaritiesBelongs to the TGF-beta family. GDNF subfamily.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Neurturin antibody
    • Neurturin precursor antibody
    • NRTN antibody
    • NRTN_HUMAN antibody
    • NTN antibody
    • prepro-neurturin antibody
    see all

Anti-Neurturin antibody images

  • Immunohistochemistry (Formalin-fixed paraffin embedded sections) of human brain tissue labeling Neurturin with Anti-Neurturin antibody (ab8061) at 5μg/ml.
  • All lanes : Anti-Neurturin antibody (ab8061) at 1/500 dilution

    Lane 1 : 10ng full length recombinant Neurturin in HeLa cell lysate
    Lane 2 : 2.5ng full length recombinant Neurturin in HeLa cell lysate
  • ab8061 at 5µg/ml staining Neurturin in human brain tissue by IHC.

References for Anti-Neurturin antibody (ab8061)

This product has been referenced in:
  • Wang K  et al. The neurotrophic factor neurturin contributes toward an aggressive cancer cell phenotype, neuropathic pain and neuronal plasticity in pancreatic cancer. Carcinogenesis N/A:N/A (2013). IHC ; Human . Read more (PubMed: 24067900) »
  • Demir IE  et al. Neuronal plasticity in chronic pancreatitis is mediated via the neurturin/GFRa2 axis. Am J Physiol Gastrointest Liver Physiol 303:G1017-28 (2012). IHC ; Human . Read more (PubMed: 22961804) »

See all 2 Publications for this product

Product Wall

Application Western blot
Sample Human Recombinant protein (Extracts of transfected hNRTN COS-1 cells)
Gel Running Conditions Reduced Denaturing
Loading amount 15 µg
Specification Extracts of transfected hNRTN COS-1 cells
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 3% · Temperature: 25°C

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Verified customer

Submitted Aug 07 2015

Vielen Dank für Ihren Anruf.

Es tut mir leid, dass Sie Probleme mit diesem Antikörper hatten. Wie am Telefon besprochen, habe ich eine kostenlose Ersatzlieferung für Sie in Auftrag gegeben. Sie hat die Referenznummer xx und so...

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