Overview

  • Product name
    Anti-Newcastle Disease virus antibody
    See all Newcastle Disease virus primary antibodies
  • Description
    Chicken polyclonal to Newcastle Disease virus
  • Tested applications
    Suitable for: ELISA, ICC/IFmore details
  • Species reactivity
    Monospecific for Newcastle Disease.
  • Immunogen

    Avian paramyxovirus serotype 1 (Newcastle disease virus) strain LaSota

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 40% Glycerol
  • Purity
    Whole antiserum
  • Purification notes
    Monospecific antiserum produced in SPF (Specific Pathogen Free) chicken
  • Clonality
    Polyclonal
  • Isotype
    IgY
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab34402 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
ICC/IF Use at an assay dependent concentration. PubMed: 22357510

Target

  • Relevance
    Newcastle disease is a highly contagious bird disease affecting many domestic and wild avian species, most notably in domestic poultry. Newcastle disease is caused by Newcastle disease virus (NDV) a negative sense single stranded RNA virus. Transmission occurs by exposure to faecal and other excretions from infected birds. Exposure to humans can cause mild conjunctivitis and influenza like symptoms, but otherwise causes no hazzard to health. NDV has the potential to be used as an anti-cancer agent. There are many different strains of NDV, and they have been classified as either lytic or nonlytic for human cells. Lytic strains and nonlytic strains both appear to replicate much more efficiently in human cancer cells than they do in most normal human cells, however, both classifications of NDV have the ability to selectively kill human tumour cells with limited toxicity to normal cells.
  • Alternative names
    • NDV antibody

References

This product has been referenced in:
  • Buijs PR  et al. Different responses of human pancreatic adenocarcinoma cell lines to oncolytic Newcastle disease virus infection. Cancer Gene Ther 21:24-30 (2014). Read more (PubMed: 24384773) »
  • Beier R  et al. Isolation of more potent oncolytic paramyxovirus by bioselection. Gene Ther : (2012). ICC/IF . Read more (PubMed: 22357510) »

See all 2 Publications for this product

Customer reviews and Q&As

Thank you for contacting us.

We unfortunately haven't tested this antibody with strain other than La Sota so I am sorry we were not be able to confirm the specificity this time. Alternatively if you are interested in testing this antibody with...

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Thank you for contacting Abcam

Concerning ab34402,Newcastle Disease Virus (NDV) Pab Chicken x:



1. Theconcentration has not been determined because it is serum level purity. Theantibody itself has not been purified from se...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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