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Synthetic peptide corresponding to Human NF-kB p65 aa 538-546.
NF-kB (nuclear factor kB) regulates the expression of a large number of genes that play critical roles in apoptosis, viral replication, tumorigenesis, various autoimmune diseases and inflammation. The active nuclear form of the NFkB transcription factor complex is composed of two DNA binding subunits, NF-kB p65 and p50, both of which share extensive N terminal sequence homology with the v-rel oncogene product. N terminal regions of p50 and p65 are critical for DNA binding and help determine the DNA binding specificities of p50 and p65.
Our Abpromise guarantee covers the use of ab17742 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Detects a band of approximately 65 kDa (predicted molecular weight: 65 kDa).|
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"