Validated using a knockout cell line

Anti-NF-kB p65 antibody [E379] (ab32536)

Publishing research using ab32536? Please let us know so that we can cite the reference in this datasheet.

ab32536 has been referenced in 50 publications.

  • Wen H  et al. Recurrent ECSIT mutation encoding V140A triggers hyperinflammation and promotes hemophagocytic syndrome in extranodal NK/T cell lymphoma. Nat Med 24:154-164 (2018). WB . PubMed: 29291352
  • Saito K  et al. Xanthohumol inhibits angiogenesis by suppressing nuclear factor-?B activation in pancreatic cancer. Cancer Sci 109:132-140 (2018). PubMed: 29121426
  • Ding Y  et al. Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation. Cell Death Dis 9:386 (2018). PubMed: 29515165
  • Liu XY  et al. Neferine Protects Endothelial Glycocalyx via Mitochondrial ROS in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome. Front Physiol 9:102 (2018). PubMed: 29520236
  • Jin Y  et al. Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated aging. Sci Rep 8:5145 (2018). WB . PubMed: 29572511
  • Sun JC  et al. Overexpression of ß-Arrestin1 in the Rostral Ventrolateral Medulla Downregulates Angiotensin Receptor and Lowers Blood Pressure in Hypertension. Front Physiol 9:297 (2018). PubMed: 29643817
  • Balan I  et al. The GABAA Receptor a2 Subunit Activates a Neuronal TLR4 Signal in the Ventral Tegmental Area that Regulates Alcohol and Nicotine Abuse. Brain Sci 8:N/A (2018). PubMed: 29690521
  • Du M  et al. The LPS-inducible lncRNA Mirt2 is a negative regulator of inflammation. Nat Commun 8:2049 (2017). ICC/IF . PubMed: 29230038
  • Wu C  et al. Inhibition of intimal hyperplasia in murine aortic allografts by administration of a small-molecule TLR4 inhibitor TAK-242. Sci Rep 7:15799 (2017). PubMed: 29150694
  • Luo Q  et al. Sodium fluoride induces renal inflammatory responses by activating NF-?B signaling pathway and reducing anti-inflammatory cytokine expression in mice. Oncotarget 8:80192-80207 (2017). PubMed: 29113295
  • Zeng X  et al. Acylated and unacylated ghrelin inhibit atrophy in myotubes co-cultured with colon carcinoma cells. Oncotarget 8:72872-72885 (2017). PubMed: 29069832
  • Schmidt C  et al. Acetyl-lupeolic acid inhibits Akt signaling and induces apoptosis in chemoresistant prostate cancer cellsin vitroandin vivo. Oncotarget 8:55147-55161 (2017). PubMed: 28903409
  • Xiong W  et al. Research on the effect of ginseng polysaccharide on apoptosis and cell cycle of human leukemia cell line K562 and its molecular mechanisms. Exp Ther Med 13:924-934 (2017). PubMed: 28450921
  • Deng H  et al. Sodium fluoride induces apoptosis in mouse splenocytes by activating ROS-dependent NF-?B signaling. Oncotarget 8:114428-114441 (2017). PubMed: 29383091
  • Liu J  et al. Lipopolysaccharide Stimulates Surfactant Protein-A in Human Renal Epithelial HK-2 Cells through Upregulating Toll-like Receptor 4 Dependent MEK1/2-ERK1/2-NF-?B Pathway. Chin Med J (Engl) 130:1236-1243 (2017). PubMed: 28485325
  • Tian J  et al. Correlation between NF-?B signal pathway-mediated caspase-4 activation and Kawasaki disease. Exp Ther Med 13:3333-3336 (2017). PubMed: 28587409
  • Yi L  et al. Inflammation-mediated SOD-2 upregulation contributes to epithelial-mesenchymal transition and migration of tumor cells in aflatoxin G1-induced lung adenocarcinoma. Sci Rep 7:7953 (2017). PubMed: 28801561
  • Zhang L  et al. Neuron-derived CCL2 contributes to microglia activation and neurological decline in hepatic encephalopathy. Biol Res 50:26 (2017). WB ; Rat . PubMed: 28870240
  • Zhang HM  et al. Role of ?133p53 isoform in NF-?B inhibitor PDTC-mediated growth inhibition of MKN45 gastric cancer cells. World J Gastroenterol 23:2716-2722 (2017). ICC/IF ; Human . PubMed: 28487608
  • Fujii U  et al. Effect of a retinoid X receptor partial agonist on airway inflammation and hyperresponsiveness in a murine model of asthma. Respir Res 18:23 (2017). WB ; Mouse . PubMed: 28114934
  • Ravindran D  et al. Chemokine binding protein 'M3' limits atherosclerosis in apolipoprotein E-/- mice. PLoS One 12:e0173224 (2017). WB ; Mouse . PubMed: 28282403
  • Wang B  et al. IL-34 Upregulated Th17 Production through Increased IL-6 Expression by Rheumatoid Fibroblast-Like Synoviocytes. Mediators Inflamm 2017:1567120 (2017). WB ; Human . PubMed: 28659662
  • Sweeney EL  et al. Ureaplasma Species Multiple Banded Antigen (MBA) Variation Is Associated with the Severity of Inflammation In vivo and In vitro in Human Placentae. Front Cell Infect Microbiol 7:123 (2017). WB ; Human . PubMed: 28451522
  • Ali AA  et al. Erlotinib-Conjugated Iron Oxide Nanoparticles as a Smart Cancer-Targeted Theranostic Probe for MRI. Sci Rep 6:36650 (2016). WB, ICC . PubMed: 27833124
  • Li C  et al. Qishen granules inhibit myocardial inflammation injury through regulating arachidonic acid metabolism. Sci Rep 6:36949 (2016). WB . PubMed: 27833128
  • Jeon M  et al. Elevated IL-1ß expression induces invasiveness of triple negative breast cancer cells and is suppressed by zerumbone. Chem Biol Interact 258:126-33 (2016). PubMed: 27567548
  • Bai D  et al. Hyperglycemia and hyperlipidemia blunts the Insulin-Inpp5f negative feedback loop in the diabetic heart. Sci Rep 6:22068 (2016). WB . PubMed: 26908121
  • Fazalul Rahiman SS  et al. Dynorphin 1-17 and Its N-Terminal Biotransformation Fragments Modulate Lipopolysaccharide-Stimulated Nuclear Factor-kappa B Nuclear Translocation, Interleukin-1beta and Tumor Necrosis Factor-alpha in Differentiated THP-1 Cells. PLoS One 11:e0153005 (2016). Human . PubMed: 27055013
  • Ali AA  et al. Novel Anthra[1,2-c][1,2,5]Thiadiazole-6,11-Diones as Promising Anticancer Lead Compounds: Biological Evaluation, Characterization & Molecular Targets Determination. PLoS One 11:e0154278 (2016). WB, ICC/IF . PubMed: 27100886
  • Shopsowitz KE  et al. Periodic-shRNA molecules are capable of gene silencing, cytotoxicity and innate immune activation in cancer cells. Nucleic Acids Res 44:545-57 (2016). Human . PubMed: 26704983
  • Zheng CF  et al. A20 inhibits lipopolysaccharide-induced inflammation in enterocytes. World J Gastrointest Pharmacol Ther 7:540-549 (2016). PubMed: 27867687
  • Lin JJ  et al. Toll-like receptor 4 signaling in neurons of trigeminal ganglion contributes to nociception induced by acute pulpitis in rats. Sci Rep 5:12549 (2015). WB ; Rat . PubMed: 26224622
  • Lee CC  et al. Novel inhibitors of RANKL-induced osteoclastogenesis: Design, synthesis, and biological evaluation of 6-(2,4-difluorophenyl)-3-phenyl-2H-benzo[e][1,3]oxazine-2,4(3H)-diones. Bioorg Med Chem 23:4522-32 (2015). WB ; Mouse . PubMed: 26081760
  • Belharazem D  et al. cFLIP overexpression in T cells in thymoma-associated myasthenia gravis. Ann Clin Transl Neurol 2:894-905 (2015). WB ; Human . PubMed: 26401511
  • Babini G  et al. In vitro ?-ray-induced inflammatory response is dominated by culturing conditions rather than radiation exposures. Sci Rep 5:9343 (2015). ICC/IF ; Human . PubMed: 25791775
  • Wang Y  et al. MicroRNA-181b stimulates inflammation via the nuclear factor-?B signaling pathway in vitro. Exp Ther Med 10:1584-1590 (2015). PubMed: 26622531
  • Hu S  et al. Isorhamnetin inhibits cell proliferation and induces apoptosis in breast cancer via Akt and mitogen-activated protein kinase kinase signaling pathways. Mol Med Rep 12:6745-51 (2015). Human . PubMed: 26502751
  • Ju XN  et al. Baicalin protects against thrombin induced cell injury in SH-SY5Y cells. Int J Clin Exp Pathol 8:14021-7 (2015). WB ; Human . PubMed: 26823714
  • Parker M  et al. C11orf95-RELA fusions drive oncogenic NF-?B signalling in ependymoma. Nature 506:451-5 (2014). WB . PubMed: 24553141
  • Yan M  et al. IKKa restoration via EZH2 suppression induces nasopharyngeal carcinoma differentiation. Nat Commun 5:3661 (2014). PubMed: 24739462
  • Manganaro L  et al. Tumor Suppressor Cylindromatosis (CYLD) Controls HIV Transcription in an NF-?B-Dependent Manner. J Virol 88:7528-40 (2014). Human . PubMed: 24760882
  • Li R  et al. Imbalanced network biomarkers for traditional Chinese medicine Syndrome in gastritis patients. Sci Rep 3:1543 (2013). IHC-P ; Human . PubMed: 23529020
  • Lin DP  et al. Assessment of ultraviolet B-blocking effects of weekly disposable contact lenses on corneal surface in a mouse model. Mol Vis 19:1158-68 (2013). IHC-P ; Mouse . PubMed: 23734085
  • Liu Y  et al. IL-17 contributes to cardiac fibrosis following experimental autoimmune myocarditis by a PKCß/Erk1/2/NF-?B-dependent signaling pathway. Int Immunol 24:605-12 (2012). PubMed: 22531062
  • Bel S  et al. Loss of TMF/ARA160 protein renders colonic mucus refractory to bacterial colonization and diminishes intestinal susceptibility to acute colitis. J Biol Chem 287:25631-9 (2012). IHC-P ; Mouse . PubMed: 22553199
  • Chen BY  et al. Dietary zerumbone prevents mouse cornea from UVB-induced photokeratitis through inhibition of NF-?B, iNOS, and TNF-a expression and reduction of MDA accumulation. Mol Vis 17:854-63 (2011). IHC-P ; Mouse . PubMed: 21527993
  • Herkenham M  et al. Cautionary notes on the use of NF-?B p65 and p50 antibodies for CNS studies. J Neuroinflammation 8:141 (2011). WB ; Mouse . PubMed: 21999414
  • Niculescu LS  et al. Apolipoprotein A-I stimulates cholesteryl ester transfer protein and apolipoprotein E secretion from lipid-loaded macrophages; the role of NF-?B and PKA signaling pathways. Biochem Biophys Res Commun 415:497-502 (2011). WB ; Human . PubMed: 22056562
  • Souslova V  et al. Allele-specific regulation of matrix metalloproteinase-3 gene by transcription factor NFkappaB. PLoS One 5:e9902 (2010). IHC-P ; Human . PubMed: 20360864
  • Huang Y & Ratovitski EA Phosphorylated TP63 induces transcription of RPN13, leading to NOS2 protein degradation. J Biol Chem 285:41422-31 (2010). WB ; Human . PubMed: 20959455


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