Anti-NFAT5 antibody (ab110995)
Key features and details
- Rabbit polyclonal to NFAT5
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NFAT5 antibody
See all NFAT5 primary antibodies -
Description
Rabbit polyclonal to NFAT5 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Synthesized peptide derived from the internal region of Human NFAT5.
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Positive control
- Human breast carcinoma tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), PBS, 0.88% Sodium chloride -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab110995 is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab110995 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Plays a role in the inducible expression of genes. Regulates hypertonicity-induced cellular accumulation of osmolytes. -
Tissue specificity
Highest levels in skeletal muscle, brain, heart and peripheral blood leukocytes. Also expressed in placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon. -
Sequence similarities
Contains 1 RHD (Rel-like) domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 10725 Human
- Entrez Gene: 54446 Mouse
- Omim: 604708 Human
- SwissProt: O94916 Human
- SwissProt: Q9WV30 Mouse
- Unigene: 371987 Human
- Unigene: 390057 Mouse
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Alternative names
- Glutamine rich protein H65 antibody
- KIAA0827 antibody
- NF AT5 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab110995 has been referenced in 2 publications.
- Muhammad K et al. NFAT5 Controls the Integrity of Epidermis. Front Immunol 12:780727 (2021). PubMed: 34956208
- Jones KB et al. miRNA signatures associate with pathogenesis and progression of osteosarcoma. Cancer Res 72:1865-77 (2012). IHC-P ; Human . PubMed: 22350417