Anti-NFAT5 antibody - N-terminal (ab137407)
Key features and details
- Rabbit polyclonal to NFAT5 - N-terminal
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NFAT5 antibody - N-terminal
See all NFAT5 primary antibodies -
Description
Rabbit polyclonal to NFAT5 - N-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Chicken -
Immunogen
Recombinant fragment, corresponding to a region within N terminal amino acids 117-404 of Human NFAT5.
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Positive control
- MOLT4 and HeLa cell lysates
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab137407 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/500 - 1/3000. Predicted molecular weight: 158, 165 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 158, 165 kDa. |
Target
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Function
Plays a role in the inducible expression of genes. Regulates hypertonicity-induced cellular accumulation of osmolytes. -
Tissue specificity
Highest levels in skeletal muscle, brain, heart and peripheral blood leukocytes. Also expressed in placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon. -
Sequence similarities
Contains 1 RHD (Rel-like) domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 415866 Chicken
- Entrez Gene: 10725 Human
- Entrez Gene: 54446 Mouse
- Entrez Gene: 307820 Rat
- Omim: 604708 Human
- SwissProt: O94916 Human
- SwissProt: Q9WV30 Mouse
- Unigene: 371987 Human
see all -
Alternative names
- Glutamine rich protein H65 antibody
- KIAA0827 antibody
- NF AT5 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab137407 has been referenced in 2 publications.
- Zhang M et al. Long Noncoding RNA X-Inactive-Specific Transcript Promotes the Secretion of Inflammatory Cytokines in LPS Stimulated Astrocyte Cell Via Sponging miR-29c-3p and Regulating Nuclear Factor of Activated T cell 5 Expression. Front Endocrinol (Lausanne) 12:573143 (2021). PubMed: 33776905
- Zhang Y et al. ASIC1a induces synovial inflammation via the Ca2+/NFATc3/ RANTES pathway. Theranostics 10:247-264 (2020). PubMed: 31903118