Overview

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab4978 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Additional notes


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human NFAT5, ab3446. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • Glutamine rich protein H65
    • KIAA0827
    • NF AT5
    • NF-AT5
    • NFAT 5
    • NFAT L1
    • NFAT like protein 1
    • NFAT5
    • NFAT5_HUMAN
    • NFATL 1
    • NFATL1
    • NFATZ
    • Nuclear factor of activated T cells
    • Nuclear factor of activated T cells 5
    • Nuclear factor of activated T cells 5 tonicity responsive
    • Nuclear factor of activated T-cells 5
    • OREBP
    • Osmotic response element binding protein
    • T cell transcription factor NFAT 5
    • T cell transcription factor NFAT5
    • T-cell transcription factor NFAT5
    • TonE binding protein
    • TonE-binding protein
    • TonEBP
    • Tonicity responsive enhancer binding protein
    • Tonicity-responsive enhancer-binding protein
    see all
  • Function
    Plays a role in the inducible expression of genes. Regulates hypertonicity-induced cellular accumulation of osmolytes.
  • Tissue specificity
    Highest levels in skeletal muscle, brain, heart and peripheral blood leukocytes. Also expressed in placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon.
  • Sequence similarities
    Contains 1 RHD (Rel-like) domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References

ab4978 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Application
Western blot
Using anti-NFAT5 antibody ab3446 several bands were obtained. To verify which band is specific, the immunizing peptide ab4978 was used. Band at ~230kDa is specific (see picture)
1+2) JEG3 whole cell lysate
3) rat placenta lysate
4) rat kidney lysate

left: ab3446 1:750 + ab4978 1:750
right: ab3446 1:750
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Verified customer

Submitted Jun 13 2017

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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