FunctionRecognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
Sequence similaritiesBelongs to the CTF/NF-I family. Contains 1 CTF/NF-I DNA-binding domain.
Anti-NFIC antibody (ab89516) at 1/500 dilution + HeLa nuclear extracts at 50 µg
Predicted band size : 56 kDa
References for Anti-NFIC antibody (ab89516)
This product has been referenced in:
Li D et al. Inhibition of AHR transcription by NF1C is affected by a single-nucleotide polymorphism, and is involved in suppression of human uterine endometrial cancer. Oncogene : (2012).
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