Human Predicted to work with:
Mouse, Hamster, Xenopus laevis
Recombinant fragment corresponding to amino acids 291-390 (DDVFYPGTGR SPAAGSSQSS GWPNDVDAGP ASLKKSGKLD FCSALSSQGS SPRMAFTHHP LPVLAGVRPG SPRATASALH FPSTSIIQQS SPYFTHPTIR) of human NFIX (NP_002492) with a proprietary tag.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 55 kDa.
Use at an assay dependent dilution.
FunctionRecognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
Sequence similaritiesBelongs to the CTF/NF-I family. Contains 1 CTF/NF-I DNA-binding domain.
Ferenczy MW et al. Clonal immortalized human glial cell lines support varying levels of JC virus infection due to differences in cellular gene expression. J Neuroimmune Pharmacol8:1303-19 (2013).
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