Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Reassurance, Refunds & Replacements
If your product does not perform as described on this datasheet, we will refund or replace your product...
Read our guarantee »Overview
Product name
NG-Monomethyl-L-arginine, monoacetate salt (L-NMMA)
Description
NOS inhibitor
Alternative names
- L-NMMA
Biological description
Cell permeable competitive NOS inhibitor. (Ki values are = 700 nM, 3.9 µM and 650 nM for eNOS, iNOS and nNOS respectively).
Purity
> 99%
General notes
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Properties
Chemical name
NG-Methyl-L-arginine acetate salt
Molecular Weight
248.28
Chemical structure
Molecular formula
C7H16N4O2.CH3CO2H
CAS Number
53308-83-1
Solubility
Soluble in water to 50 mM
Storage instructions
Store at room temperature (desiccating conditions).
Research areas
Biochemicals >> Research Area >> Stroke >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Respiratory disease >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Pain & inflammation >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Obesity >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Hypertension >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Heart disease >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Diabetes >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Cancer >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Alzheimer's Disease >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Pharmacology >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Pharmacology >> Enzymes >> Synthetase & synthase >> Inhibitors
Biochemicals >> Chemical Type >> Biochemicals
Biochemicals >> Chemical Type >> Amino Acid
Biochemicals >> Product Range >> Just Add Water
References for NG-Monomethyl-L-arginine, monoacetate salt (L-NMMA) (ab120137)
This product has been referenced in:
- Cardounel AJ et al. Evidence for the pathophysiological role of endogenous methylarginines in regulation of endothelial NO production and vascular function. J Biol Chem 282:879-87 (2007).Read more (PubMed: 17082183) »
- Maggi CA et al. Effect of NG-monomethyl L-arginine (L-NMMA) and NG-nitro L-arginine (L-NOARG) on non-adrenergic non-cholinergic relaxation in the circular muscle of the human ileum. Br J Pharmacol 103:1970-2 (1991).Read more (PubMed: 1912984) »
See all 3 publications for this product
Publishing research using ab120137? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"