Overview

  • Product nameAnti-NGF antibody
    See all NGF primary antibodies
  • Description
    Goat polyclonal to NGF
  • Tested applicationsSuitable for: ELISA, WB, Neutralisingmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Recombinant full length rat NGF beta protein expressed in Sf 21 insect cells.

  • Positive control
    • Tested with human erythroleukemic cells (TF-1) expressing recombinant rat NGF beta.

Properties

Applications

Our Abpromise guarantee covers the use of ab10837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use a concentration of 0.5 - 1 µg/ml.
WB Use a concentration of 0.1 - 0.2 µg/ml. Detects a band of approximately 13.2 kDa.
Neutralising Use a concentration of 0.05 - 0.15 µg/ml.

Target

  • FunctionNerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
  • Involvement in diseaseNeuropathy, hereditary sensory and autonomic, 5
  • Sequence similaritiesBelongs to the NGF-beta family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Beta nerve growth factor antibody
    • Beta NGF antibody
    • Beta-nerve growth factor antibody
    • Beta-NGF antibody
    • HSAN5 antibody
    • MGC161426 antibody
    • MGC161428 antibody
    • Nerve growth factor (beta polypeptide) antibody
    • Nerve growth factor antibody
    • Nerve growth factor beta antibody
    • Nerve growth factor beta polypeptide antibody
    • Nerve growth factor beta subunit antibody
    • NGF antibody
    • NGF_HUMAN antibody
    • NGFB antibody
    • NID67 antibody
    see all

References for Anti-NGF antibody (ab10837)

ab10837 has not yet been referenced specifically in any publications.

Product Wall

Thank you for providing some more useful information about your experimental system. I understand now from your recent e-mail, that you used Cos-7 cells (monkey) transfected with a vector carrying the coding part of the human NGFb gene. I have disc...

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