Overview

  • Product name
  • Description
    Rabbit polyclonal to NGLY1
  • Tested applications
    Suitable for: WB, ICCmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human NGLY1 aa 100-200 (internal sequence). The exact sequence is proprietary.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: Whole serum
  • Purity
    Whole antiserum
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab73984 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200 - 1/2000. Predicted molecular weight: 74 kDa.
ICC Use at an assay dependent dilution.

Target

  • Relevance
    NGLY1 is a highly conserved enzyme that catalyzes deglycosylation of misfolded N-linked glycoproteins by cleaving the glycan chain before the proteins are degraded by the proteasome (Zhou et al., 2006).
  • Cellular localization
    Cytoplasm
  • Database links
  • Alternative names
    • CDG1V antibody
    • hPNGase antibody
    • N glycanase 1 antibody
    • NGLY 1 antibody
    • Peptide N(4) (N acetyl beta glucosaminyl asparagine amidase antibody
    • Peptide:N glycanase antibody
    • PNG1 antibody
    • PNGase antibody
    see all

References

This product has been referenced in:
  • Wu KX  et al. Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication. Nat Commun 7:13150 (2016). Read more (PubMed: 27748395) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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