Nicotinic Acetylcholine Receptor alpha 4 peptide (ab123011)

Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SequenceC-HVETRAHAEERLLKK

Associated products

Specifications

Our Abpromise guarantee covers the use of ab123011 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Nicotinic Acetylcholine Receptor alpha 4 antibody (ab77356)

  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

  • ReconstitutionResuspend in water or in neutral buffer

General Info

  • Alternative names
    • A4 nicotinic receptor
    • Acetylcholine receptor alpha 4 neural
    • Acetylcholine receptor neuronal nicotinic alpha 4 subunit
    • ACH 4
    • ACH4
    • ACHA4_HUMAN
    • AChR
    • Acra 4
    • Acra4
    • Alpha4 nAChR
    • BFNC
    • Cholinergic receptor nicotinic alpha 4
    • Cholinergic receptor nicotinic alpha polypeptide 4
    • CHRNA 4
    • CHRNA4
    • EBN
    • EBN 1
    • EBN1
    • NACHR
    • NACRA 4
    • NACRA4
    • Neuronal acetylcholine receptor subunit alpha-4
    • Neuronal nicotinic acetylcholine receptor alpha 4 subunit
    see all
  • FunctionAfter binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  • Involvement in diseaseDefects in CHRNA4 are the cause of nocturnal frontal lobe epilepsy type 1 (ENFL1) [MIM:600513]; also symbolized ADNFLE. ENFL1 is an autosomal dominant epilepsy characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements.
  • Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-4/CHRNA4 sub-subfamily.
  • Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt

References for Nicotinic Acetylcholine Receptor alpha 4 peptide (ab123011)

ab123011 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry.

The molecular weight of the peptide was not determined.

The molecular weight of the antibody is ca 150kDa.

Molecular weight is not necessary to calculate the dilutions of the blocking peptide. C...

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Vielen Dank für Ihren Anruf. Auf Ihre Anfrage hin haben wir das Blockpeptid für den Acetylcholin-Rezeptor alpha 4 (ab77356) in unseren Katalog aufgenommen. Es hat die Artikelnummer ab123011 und kostet 175 EUR plus Versandgebühren. Click here (or ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"