Anti-Nicotinic Acetylcholine Receptor alpha 5 antibody (ab116538)

Overview

  • Product name
    Anti-Nicotinic Acetylcholine Receptor alpha 5 antibody
    See all Nicotinic Acetylcholine Receptor alpha 5 primary antibodies
  • Description
    Rabbit polyclonal to Nicotinic Acetylcholine Receptor alpha 5
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 186-216 of Human Nicotinic Acetylcholine Receptor alpha 5 (NP_000736.2).

  • Positive control
    • A549 cell line lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab116538 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab116538 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 53 kDa.

Target

  • Function
    After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  • Sequence similarities
    Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-5/CHRNA5 sub-subfamily.
  • Cellular localization
    Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Acetylcholine receptor nicotinic alpha 5 (neuronal) antibody
    • ACHA5_HUMAN antibody
    • AChR antibody
    • Cholinergic receptor neuronal nicotinic alpha polypeptide 5 antibody
    • Cholinergic receptor nicotinic alpha 5 antibody
    • Cholinergic receptor nicotinic alpha polypeptide 5 antibody
    • CHRNA 5 antibody
    • CHRNA5 antibody
    • LNCR2 antibody
    • NACHRA 5 antibody
    • NACHRA5 antibody
    • Neuronal acetylcholine receptor subunit alpha 5 antibody
    • Neuronal acetylcholine receptor subunit alpha-5 antibody
    • Neuronal nicotinic acetylcholine receptor alpha 5 subunit antibody
    • Neuronal nicotinic acetylcholine receptor, alpha5 subunit antibody
    • OTTHUMP00000185019 antibody
    see all

Images

  • Anti-Nicotinic Acetylcholine Receptor alpha 5 antibody (ab116538) at 1/100 dilution + A549 cell line lysate at 35 µg

    Predicted band size : 53 kDa

References

ab116538 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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