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Rabbit polyclonal to Nicotinic Acetylcholine Receptor beta 4 - C-terminal
Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 422-450 of Human Nicotinic Acetylcholine Receptor beta 4 (NP_000741.1)
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle. Store undiluted.
Preservative: 0.09% Sodium azide
Constituent: 99.91% PBS
Concentration information loading...
Immunogen affinity purified
ab156213 is purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 56 kDa.
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta-4/CHRNB4 sub-subfamily.
Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
Information by UniProt
acetylcholine receptor, nicotinic, beta 4 (neuronal) antibody
This product has been referenced in:
et al. Secreted Isoform of Human Lynx1 (SLURP-2): Spatial Structure and Pharmacology of Interactions with Different Types of Acetylcholine Receptors. Sci Rep 6:30698 (2016).
Read more (PubMed: 27485575) »
et al. Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1) Is a Selective Allosteric Antagonist of a7 Nicotinic Acetylcholine Receptor. PLoS One 11:e0149733 (2016).
Read more (PubMed: 26905431) »
See all 2 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"