Overview

  • Product nameNicotinic acid (Niacin)
  • Description
    Antidyslipidemic agent
  • Alternative names
    • Niacin
    • vitamin B3
  • Biological descriptionAntidyslipidemic. Increases high-density- and lowers low-density lipoproteins. Putative ligand for the HM74A receptor.
  • Purity> 98%

Properties

    Applications

    Our Abpromise guarantee covers the use of ab120145 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Functional Studies Use at an assay dependent concentration.

    Nicotinic acid (Niacin) images

    • ab64308 staining ApoA1 in HepG1 cells treated with nicotinic acid (ab120145), by ICC/IF. Decrease in ApoA1 expression correlates with increased concentration of nicotinic acid, as described in literature.
      The cells were incubated at 37°C for 72h in media containing different concentrations of ab120145 (nicotinic acid) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab64308 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody.

    References for Nicotinic acid (Niacin) (ab120145)

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