Overview

  • Product nameAnti-NIPSNAP1 antibody
    See all NIPSNAP1 primary antibodies
  • Description
    Rabbit polyclonal to NIPSNAP1
  • Tested applicationsSuitable for: ICC/IF, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (Human) of 18 amino acids from near the C-terminus.

  • Positive control
    • Human Brain Tissue Lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab67302 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use a concentration of 2.5 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).

Target

  • RelevanceNIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP’s expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.
  • Cellular localizationMitochondrial
  • Database links
  • Alternative names
    • NIPSNAP 1 antibody
    • Nipsnap homolog 1 (C. elegans) antibody
    • Protein NipSnap homolog 1 antibody

Anti-NIPSNAP1 antibody images

  • Lane 1 : Anti-NIPSNAP1 antibody (ab67302) at 0.5 µg/ml
    Lane 2 : Anti-NIPSNAP1 antibody (ab67302) at 1 µg/ml

    Lane 1 : Human brain tissue lysate
    Lane 2 : Human brain tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 33 kDa
    Observed band size : 33 kDa
  • ab67302 at 2.5 µg/ml staining NIPSNAP1 in human prostate tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).

  • Immunofluorescence of NIPSNAP in Human Brain cells using ab67302 at 20 ug/ml.

References for Anti-NIPSNAP1 antibody (ab67302)

This product has been referenced in:

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"