Overview

  • Product name
    Anti-Nitro tyrosine antibody
    See all Nitro tyrosine primary antibodies
  • Description
    Goat polyclonal to Nitro tyrosine
  • Specificity
    Specifically binds to nitro-LDL and other nitrated proteins.
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Immunogen

    Pure nitrated Keyhole Limpet Hemocyanin (NY-KLH).

Properties

Applications

Our Abpromise guarantee covers the use of ab20117 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    ELISA: 1/20000 - 1/160000. WB: 1/20000 - 1/160000. Dilution optimised using Chromogenic detection. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      Nitric oxide (NO) is a product of the enzymatic conversion of arginine to citrulline by nitric oxide synthase. NO reacts rapidly with superoxide to form peroxynitrite. At physiological pH and in the presence of transition metals, peroxynitrite undergoes heterolytic cleavage to form hydroxyl anion and nitronium ion, the latter of which nitrates protein tyrosine residues. Thus, the presence of nitrotyrosine on proteins can be used as a marker for peroxynitrite formation in vivo. The presence of nitrotyrosine has been detected in various inflammatory processes including atherosclerotic placques.
    • Alternative names
      • NO tyrosine antibody
      • nTyr antibody

    References

    ab20117 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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