Anti-Nitro tyrosine antibody (FITC) (ab27647)

Overview

  • Product nameAnti-Nitro tyrosine antibody (FITC)
    See all Nitro tyrosine primary antibodies
  • Description
    Goat polyclonal to Nitro tyrosine (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • SpecificitySpecifically binds to nitrated proteins. Molar F/P ratio is 4.6.
  • Tested applicationsSuitable for: ICC/IFmore details
  • Immunogen

    Chemical/ Small Molecule (Nitrtyrosine modified protein)

Properties

Applications

Our Abpromise guarantee covers the use of ab27647 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent dilution.

Target

  • RelevanceNitric oxide (NO) is a product of the enzymatic conversion of arginine to citrulline by nitric oxide synthase. NO reacts rapidly with superoxide to form peroxynitrite. At physiological pH and in the presence of transition metals, peroxynitrite undergoes heterolytic cleavage to form hydroxyl anion and nitronium ion, the latter of which nitrates protein tyrosine residues. Thus, the presence of nitrotyrosine on proteins can be used as a marker for peroxynitrite formation in vivo. The presence of nitrotyrosine has been detected in various inflammatory processes including atherosclerotic placques.
  • Alternative names
    • NO tyrosine antibody
    • nTyr antibody

References for Anti-Nitro tyrosine antibody (FITC) (ab27647)

ab27647 has not yet been referenced specifically in any publications.

Product Wall


I am very pleased to hear you would like to accept our offer and test ab27647 in IHC. This code will give you ab27647 off your next order before the expiration date. To redeem this offer, please submit an Abreview forIHC and include this code in t...

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Thank you for contacting Abcam.

To our knowledge, ab27647 has not been tested in IHC, it has only been tested in ICC/IF, therefore we cannot guarantee that it willwork inthisapplication, so it is not covered under our Abpromise.

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