Overview

  • Product nameAnti-NK1.1 antibody [PK136] (FITC)
    See all NK1.1 primary antibodies
  • Description
    Mouse monoclonal [PK136] to NK1.1 (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • SpecificityThis antibody is specific to Mouse NK1.1 alloantigen, Mr 80-85 kDa (39 kDa under reducing conditions).
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Tissue, cells or virus corresponding to NK1.1. CE mouse spleen enriched for NK-1+ cells and bone marrow cells

Properties

Applications

Our Abpromise guarantee covers the use of ab25026 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

Target

  • FunctionPlays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization and interferon-gamma production.
  • Tissue specificityExpressed in natural killer cells.
  • Sequence similaritiesContains 1 C-type lectin domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD161 antigen like family member C antibody
    • CD161 antigen-like family member C antibody
    • CD161c antibody
    • Killer cell lectin-like receptor subfamily B member 1C antibody
    • Klrb1c antibody
    • Klrb1f antibody
    • KLRBC_MOUSE antibody
    • Ly-55c antibody
    • Ly55c antibody
    • Lymphocyte antigen 55c antibody
    • Lymphocyte antigen 59 antibody
    • Natural killer cell surface protein P1-40 antibody
    • NK1.1 antibody
    • NKR P1.9 antibody
    • NKR P1C antibody
    • NKR-P1 40 antibody
    • NKR-P1.9 antibody
    • NKR-P1C antibody
    • NKRP1 antibody
    see all

References for Anti-NK1.1 antibody [PK136] (FITC) (ab25026)

This product has been referenced in:
  • McAllister CS  et al. TLR3, TRIF, and caspase 8 determine double-stranded RNA-induced epithelial cell death and survival in vivo. J Immunol 190:418-27 (2013). ICC/IF . Read more (PubMed: 23209324) »
  • Karlhofer FM & Yokoyama WM Stimulation of murine natural killer (NK) cells by a monoclonal antibody specific for the NK1.1 antigen. IL-2-activated NK cells possess additional specific stimulation pathways. J Immunol 146:3662-73 (1991). Read more (PubMed: 2026886) »

See all 5 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"