Anti-NK1.1 antibody [PK136] (Phycoerythrin) (ab25027)

Overview

  • Product name
    Anti-NK1.1 antibody [PK136] (Phycoerythrin)
    See all NK1.1 primary antibodies
  • Description
    Mouse monoclonal [PK136] to NK1.1 (Phycoerythrin)
  • Conjugation
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • Tested applications
    Suitable for: Flow Cyt, IP, Cellular Activationmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Tissue/ cell preparation: CD spleen and bone marrow cells enriched for NK1+ cells (Mouse).

  • Positive control
    • Flow Cyt: Mouse spleen cells.
  • General notes

    This antibody can be used for in vitro complement dependent cytotoxicity assays, in vivo depletion and in vitro activation of NK1.1 cells and in vitro redirected lysis.

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

Properties

Applications

Our Abpromise guarantee covers the use of ab25027 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.
IP Use at an assay dependent concentration.
Cellular Activation Use at an assay dependent concentration.

Target

  • Function
    Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization and interferon-gamma production.
  • Tissue specificity
    Expressed in natural killer cells.
  • Sequence similarities
    Contains 1 C-type lectin domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD161 antigen like family member C antibody
    • CD161 antigen-like family member C antibody
    • CD161c antibody
    • Killer cell lectin-like receptor subfamily B member 1C antibody
    • Klrb1c antibody
    • Klrb1f antibody
    • KLRBC_MOUSE antibody
    • Ly-55c antibody
    • Ly55c antibody
    • Lymphocyte antigen 55c antibody
    • Lymphocyte antigen 59 antibody
    • Natural killer cell surface protein P1-40 antibody
    • NK1.1 antibody
    • NKR P1.9 antibody
    • NKR P1C antibody
    • NKR-P1 40 antibody
    • NKR-P1.9 antibody
    • NKR-P1C antibody
    • NKRP1 antibody
    see all

Images

  • C57Bl/6 splenocytes stained with APC-conjugated anti-CD3e and 0.5µg ab25027 (right) or 0.5µg PE-conjugated mouse IgG2a isotype control (left).

References

ab25027 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab25027.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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