Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab16295 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 47 kDa.

Target

  • Function
    Acts as a transcriptional repressor. Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T cell development. Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch-regulated SKP2 promoter.
  • Sequence similarities
    Belongs to the UPF0396 family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • NF-kappa-B-activating protein antibody
    • NFKB activating protein antibody
    • Nkap antibody
    • NKAP_HUMAN antibody
    • Nuclear NF kappaB activating protein antibody
    see all

References

ab16295 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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