Anti-NKG2A + C+ E antibody [20d5] (Biotin) (ab24849)

Overview

  • Product nameAnti-NKG2A + C+ E antibody [20d5] (Biotin)
    See all NKG2A + C+ E primary antibodies
  • Description
    Rat monoclonal [20d5] to NKG2A + C+ E (Biotin)
  • ConjugationBiotin
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    CHO cells transfected with murine NKG2

  • Epitopeab24849 reacts with an epitope common to the NKG2A, NKG2C and NKG2E isoforms of the CD94/NKG2 heterodimer.
  • General notes


    Two-color immunofluorescent staining with the 20d5 antibody reveals two distinct NKG2+ phenotypes within the NK1.1+CD3- spleen cell population: NKG2hi (50%) and NKG2low (50%).

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Primary antibody notesTwo-color immunofluorescent staining with the 20d5 antibody reveals two distinct NKG2+ phenotypes within the NK1.1+CD3- spleen cell population: NKG2hi (50%) and NKG2low (50%).
  • ClonalityMonoclonal
  • Clone number20d5
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab24849 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 1µg for 106 cells. ab18445-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

Target

  • RelevanceNKG2A, NKG2C and NKG2E, are isoforms of the NKG2 lectin-like family. In mice, NKG2 subunits associate with CD94 to form heterodimers at the surface of natural killer (NK) cells.The CD94/NKG2 heterodimer is the receptor for a non-classical MHC class I ligand, which is Qa 1 in the mouse. NKG2 is expressed on NK cells, lymphokine-activated killer (LAK) T cells, and some CD8+ memory T cells.
  • Cellular localizationType II membrane protein.
  • Database links
  • Alternative names
    • KLRC1 antibody
    • KLRC2 antibody
    • KLRC3 antibody
    • NK cell receptor A antibody
    • NK cell receptor C antibody
    • NK cell receptor E antibody
    • NKG2 A activating NK receptor antibody
    • NKG2 A type II integral membrane protein antibody
    • NKG2 C activating NK receptor antibody
    • NKG2 C type II integral membrane protein antibody
    • NKG2 E activating NK receptor antibody
    • NKG2 E type II integral membrane protein antibody
    see all

References for Anti-NKG2A + C+ E antibody [20d5] (Biotin) (ab24849)

ab24849 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"