Anti-NKG2D antibody [1D11] (ab35033)

Overview

• Product nameAnti-NKG2D antibody [1D11]
  See all NKG2D primary antibodies
• Description
  Mouse monoclonal [1D11] to NKG2D
• Specificityab35033 is specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1).
• Tested applicationsSuitable for: Flow Cyt, IHC-Fr, IP, Functional Studiesmore details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  NKL cells (Human)

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
• Storage bufferPreservative: 0.09% Sodium Azide
  Constituents: PBS, pH 7.4
• Concentration information loading...
• PurityProtein G purified
• ClonalityMonoclonal
• Clone number1D11
• IsotypeIgG1
• Research areas
  • Immunology
  • Cell Type Markers
  • CD
  • NK Cells

Associated products

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

Applications

Target

• FunctionReceptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.
• Tissue specificityNatural killer cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Also detected in gamma-delta cells and CD8+ alpha-beta T-cells. Expressed in interferon-producing killer dendritic cells (IKDCs).
• Sequence similaritiesContains 1 C-type lectin domain.
• Cellular localizationMembrane.

• Target information above from: UniProt accession P26718 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 100528032 Human
  • Entrez Gene: 22914 Human
  • Omim: 611817 Human
  • SwissProt: P26718 Human
  • Unigene: 387787 Human
• Alternative names
  • CD314 antibody
  • CD314 antigen antibody
  • D12S2489E antibody

  • Killer cell lectin like receptor subfamily K member 1 antibody
  • Killer cell lectin-like receptor subfamily K member 1 antibody
  • KLR antibody
  • KLRC4 KLRK1 readthrough antibody
  • KLRK1 antibody
  • NK cell receptor D antibody
  • NK lectin-like receptor antibody
  • NKG2 D activating NK receptor antibody
  • NKG2 D type II integral membrane protein antibody
  • NKG2-D antibody
  • NKG2-D type II integral membrane protein antibody
  • NKG2-D-activating NK receptor antibody
  • Nkg2d antibody
  • NKG2D_HUMAN antibody
  • NKLLR antibody
  • NKR P2 antibody
  • Nkrp2 antibody

  see all