The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1 - 1/10. ab91356-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
FunctionReceptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.
Tissue specificityNatural killer cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Also detected in gamma-delta cells and CD8+ alpha-beta T-cells. Expressed in interferon-producing killer dendritic cells (IKDCs).
Killer cell lectin like receptor subfamily K member 1 antibody
Killer cell lectin-like receptor subfamily K member 1 antibody
NK cell receptor D antibody
NK lectin-like receptor antibody
NKG2 D activating NK receptor antibody
NKG2 D type II integral membrane protein antibody
NKG2-D type II integral membrane protein antibody
NKG2-D-activating NK receptor antibody
NKR P2 antibody
References for Anti-NKG2D antibody [1D11] (FITC) (ab35035)
This product has been referenced in:
Reiners KS et al. Rescue of impaired NK cell activity in hodgkin lymphoma with bispecific antibodies in vitro and in patients. Mol Ther21:895-903 (2013).
Read more (PubMed: 23459515) »