Anti-NKG2D antibody [MM0489-10R27] (ab89807)

Overview

  • Product nameAnti-NKG2D antibody [MM0489-10R27]
    See all NKG2D primary antibodies
  • Description
    Mouse monoclonal [MM0489-10R27] to NKG2D
  • Tested applicationsSuitable for: WB, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment to extracellular domain of Human NKG2D

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesThe IgG fraction of culture supernatant was purified by Protein G affinity chromatography and filtered through a 0.2 µm filter.
  • ClonalityMonoclonal
  • Clone numberMM0489-10R27
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab89807 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 25 kDa.
Flow Cyt 1/50 - 1/100. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • FunctionReceptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.
  • Tissue specificityNatural killer cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Also detected in gamma-delta cells and CD8+ alpha-beta T-cells. Expressed in interferon-producing killer dendritic cells (IKDCs).
  • Sequence similaritiesContains 1 C-type lectin domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD314 antibody
    • CD314 antigen antibody
    • D12S2489E antibody
    • Killer cell lectin like receptor subfamily K member 1 antibody
    • Killer cell lectin-like receptor subfamily K member 1 antibody
    • KLR antibody
    • KLRK1 antibody
    • NK cell receptor D antibody
    • NK lectin-like receptor antibody
    • NKG2 D activating NK receptor antibody
    • NKG2 D type II integral membrane protein antibody
    • NKG2-D antibody
    • NKG2-D type II integral membrane protein antibody
    • NKG2-D-activating NK receptor antibody
    • Nkg2d antibody
    • NKG2D_HUMAN antibody
    • NKLLR antibody
    • NKR P2 antibody
    • Nkrp2 antibody
    see all

Anti-NKG2D antibody [MM0489-10R27] images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human placental tissue section (4µm) labelling NKG2D with ab89807. Tissue was treated with 15µg/ml Protenase K for antigen retrieval and fixed with 4% PFA. A HRP-conjugated anti-mouse IgG was used as the secondary antibody (30 minutes at room temperature) followed by DAB color development.

References for Anti-NKG2D antibody [MM0489-10R27] (ab89807)

ab89807 has not yet been referenced specifically in any publications.

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