Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceC-KVYSKEDQDLLK
    • Amino acids136 to 147

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45787 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-NKG2D antibody (ab36136)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

General Info

  • Alternative names
    • CD314
    • CD314 antigen
    • D12S2489E
    • Killer cell lectin like receptor subfamily K member 1
    • Killer cell lectin-like receptor subfamily K member 1
    • KLR
    • KLRK1
    • NK cell receptor D
    • NK lectin-like receptor
    • NKG2 D activating NK receptor
    • NKG2 D type II integral membrane protein
    • NKG2-D
    • NKG2-D type II integral membrane protein
    • NKG2-D-activating NK receptor
    • Nkg2d
    • NKG2D_HUMAN
    • NKLLR
    • NKR P2
    • Nkrp2
    see all
  • FunctionReceptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.
  • Tissue specificityNatural killer cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Also detected in gamma-delta cells and CD8+ alpha-beta T-cells. Expressed in interferon-producing killer dendritic cells (IKDCs).
  • Sequence similaritiesContains 1 C-type lectin domain.
  • Cellular localizationMembrane.
  • Information by UniProt

References for NKG2D peptide (136-147) (ab45787)

ab45787 has not yet been referenced specifically in any publications.

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