Overview

  • Product nameAnti-Nkx3.1 antibody [4H4]See all Nkx3.1 primary antibodies ...
  • Description
    Mouse monoclonal [4H4] to Nkx3.1
  • Tested applicationsWB, ELISA, IHC-P, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 1-234 of Human Nkx3.1

  • Positive control
    • LNCaP cell lysate. Human prostate tissue. PC-3 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab96482 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 26 kDa.
ELISA 1/10000.
IHC-P 1/200 - 1/1000.
Flow Cyt 1/200 - 1/400.

Target

  • FunctionTranscription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
  • Tissue specificityHighly expressed in the prostate and, at a lower level, in the testis.
  • Sequence similaritiesBelongs to the NK-3 homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Post-translational
    modifications
    Ubiquitinated by TOPORS; monoubiquitinated at several residues and also polyubiquitinated on single residues.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • BAPX 2 antibody
    • BAPX2 antibody
    • Homeobox protein NK-3 homolog A antibody
    • Homeobox protein Nkx 3.1 antibody
    • Homeobox protein Nkx-3.1 antibody
    • Homeobox protein Nkx3.1 antibody
    • NK homeobox (Drosophila) family 3 A antibody
    • NK homeobox family 3 A antibody
    • NK homeobox, family 3, member A antibody
    • NK3 homeobox 1 antibody
    • NK3 transcription factor homolog A antibody
    • NK3 transcription factor related locus 1 antibody
    • NKX 3 antibody
    • Nkx 3.1 antibody
    • NKX 3A antibody
    • NKX3 1 antibody
    • NKX3 antibody
    • Nkx3-1 antibody
    • NKX3.1 antibody
    • Nkx3.1, mouse, homolog of antibody
    • NKX31_HUMAN antibody
    • NKX3A antibody
    see all

Anti-Nkx3.1 antibody [4H4] images

  • Anti-Nkx3.1 antibody [4H4] (ab96482) at 1/500 dilution + LNCaP cell lysate

    Predicted band size : 26 kDa
  • Immunohistochemical analysis of paraffin-embedded Human prostate tissues (A, B) using ab96482 at 1/200 dilution with DAB staining.
  • Flow cytometry analysis of PC-3 cells using ab96482 at 1/200 dilution (green) and negative control (purple).

References for Anti-Nkx3.1 antibody [4H4] (ab96482)

ab96482 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"