Overview

  • Product name
  • Description
    Mouse monoclonal to Nkx3.1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 100-210 of Human Nkx3.1

  • Positive control
  • General notes

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by July 2018 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause. 

Properties

Applications

Our Abpromise guarantee covers the use of ab55781 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
    • Tissue specificity
      Highly expressed in the prostate and, at a lower level, in the testis.
    • Sequence similarities
      Belongs to the NK-3 homeobox family.
      Contains 1 homeobox DNA-binding domain.
    • Post-translational
      modifications
      Ubiquitinated by TOPORS; monoubiquitinated at several residues and also polyubiquitinated on single residues.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • BAPX 2 antibody
      • BAPX2 antibody
      • Homeobox protein NK-3 homolog A antibody
      • Homeobox protein Nkx 3.1 antibody
      • Homeobox protein Nkx-3.1 antibody
      • Homeobox protein Nkx3.1 antibody
      • NK homeobox (Drosophila) family 3 A antibody
      • NK homeobox family 3 A antibody
      • NK homeobox, family 3, member A antibody
      • NK3 homeobox 1 antibody
      • NK3 transcription factor homolog A antibody
      • NK3 transcription factor related locus 1 antibody
      • NKX 3 antibody
      • Nkx 3.1 antibody
      • NKX 3A antibody
      • NKX3 1 antibody
      • NKX3 antibody
      • Nkx3-1 antibody
      • NKX3.1 antibody
      • Nkx3.1, mouse, homolog of antibody
      • NKX31_HUMAN antibody
      • NKX3A antibody
      see all

    Anti-Nkx3.1 antibody images



    • Predicted band size : 26 kDa
      Nkx3.1 antibody (ab55781) at 1ug/lane + NIH/3T3 cell lysate at 25ug/lane.

    References for Anti-Nkx3.1 antibody (ab55781)

    This product has been referenced in:
    • Daniels G  et al. TBLR1 as an androgen receptor (AR) coactivator selectively activates AR target genes to inhibit prostate cancer growth. Endocr Relat Cancer 21:127-42 (2014). WB ; Human . Read more (PubMed: 24243687) »
    • Bohmer M  et al. Structural Analysis of microRNA-Target Interaction by Sequential Seed Mutagenesis and Stem-Loop 3' RACE. PLoS One 8:e81427 (2013). WB ; Human . Read more (PubMed: 24282594) »

    See all 2 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab55781.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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