Overview

  • Product nameAnti-Nkx3.1 antibody
    See all Nkx3.1 primary antibodies
  • Description
    Rabbit polyclonal to Nkx3.1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Guinea pig, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal residues 180 - 229 (KRKQLSSELG DLEKHSSLPA LKEEAFSRAS LVSVYNSYPY YPYLYCVGSW) of Human Nkx3.1 (NP_006158)

  • Positive control
    • 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab83973 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 26 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionTranscription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
  • Tissue specificityHighly expressed in the prostate and, at a lower level, in the testis.
  • Sequence similaritiesBelongs to the NK-3 homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Post-translational
    modifications
    Ubiquitinated by TOPORS; monoubiquitinated at several residues and also polyubiquitinated on single residues.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • BAPX 2 antibody
    • BAPX2 antibody
    • Homeobox protein NK-3 homolog A antibody
    • Homeobox protein Nkx 3.1 antibody
    • Homeobox protein Nkx-3.1 antibody
    • Homeobox protein Nkx3.1 antibody
    • NK homeobox (Drosophila) family 3 A antibody
    • NK homeobox family 3 A antibody
    • NK homeobox, family 3, member A antibody
    • NK3 homeobox 1 antibody
    • NK3 transcription factor homolog A antibody
    • NK3 transcription factor related locus 1 antibody
    • NKX 3 antibody
    • Nkx 3.1 antibody
    • NKX 3A antibody
    • NKX3 1 antibody
    • NKX3 antibody
    • Nkx3-1 antibody
    • NKX3.1 antibody
    • Nkx3.1, mouse, homolog of antibody
    • NKX31_HUMAN antibody
    • NKX3A antibody
    see all

Anti-Nkx3.1 antibody images

  • Anti-Nkx3.1 antibody (ab83973) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 26 kDa
    Observed band size : 32 kDa (why is the actual band size different from the predicted?)

References for Anti-Nkx3.1 antibody (ab83973)

ab83973 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"