Overview

  • Product name
    Anti-Nkx3.1 antibody, prediluted
    See all Nkx3.1 primary antibodies
  • Description
    Rabbit polyclonal to Nkx3.1, prediluted
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to N-terminal region of human Nkx3.1. The amino acid sequence is not available.

  • Positive control
    • Prostate carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab41861 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P:Ready-to-use for 30 min at RT. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
    • Tissue specificity
      Highly expressed in the prostate and, at a lower level, in the testis.
    • Sequence similarities
      Belongs to the NK-3 homeobox family.
      Contains 1 homeobox DNA-binding domain.
    • Post-translational
      modifications
      Ubiquitinated by TOPORS; monoubiquitinated at several residues and also polyubiquitinated on single residues.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • BAPX 2 antibody
      • BAPX2 antibody
      • Homeobox protein NK-3 homolog A antibody
      • Homeobox protein Nkx 3.1 antibody
      • Homeobox protein Nkx-3.1 antibody
      • Homeobox protein Nkx3.1 antibody
      • NK homeobox (Drosophila) family 3 A antibody
      • NK homeobox family 3 A antibody
      • NK homeobox, family 3, member A antibody
      • NK3 homeobox 1 antibody
      • NK3 transcription factor homolog A antibody
      • NK3 transcription factor related locus 1 antibody
      • NKX 3 antibody
      • Nkx 3.1 antibody
      • NKX 3A antibody
      • NKX3 1 antibody
      • NKX3 antibody
      • Nkx3-1 antibody
      • NKX3.1 antibody
      • Nkx3.1, mouse, homolog of antibody
      • NKX31_HUMAN antibody
      • NKX3A antibody
      see all

    Images

    • Ab41861 staining human Nkx3.1 in human prostrate by immunohistochemistry using formalin fixed, paraffin embedded tissue.

    References

    ab41861 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab41861.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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