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Storage instructions Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
Storage buffer Preservative: 0.09% Sodium azide Constituent: 99% PBS
Concentration information loading...
Purity Immunogen affinity purified
Purification notes Purified through a Protein A column, followed by peptide affinity purification.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 38 kDa.
Function Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in transcriptional regulation in islet beta cells. Binds to the insulin promoter and is involved in regulation of the insulin gene. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals.
Tissue specificity Pancreatic beta cells.
Sequence similarities Contains 1 homeobox DNA-binding domain.
Domain The C-terminal domain contributes to sequence-specific DNA-binding.
Cellular localization Nucleus.
Information by UniProt
Homeobox protein NK-6 homolog A antibody
Homeobox protein Nkx-6.1 antibody
NK homeo box, family 6, member A antibody
Anti-nkx6.1 antibody images
References for Anti-nkx6.1 antibody (ab123412)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"