Overview

  • Product nameAnti-NLGN4X antibody
    See all NLGN4X primary antibodies
  • Description
    Mouse monoclonal to NLGN4X
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: RVRDHYRATK VAFWLELVPH LHNLNEIFQY VSTTTKVPPP DMTSFPYGTR RSPAKIWPTT KRPAITPANN PKHSKDPHKT GPEDTTVLIE TKRDYSTELS , corresponding to amino acids 577-677 of Human Neuroligin 4

Properties

Applications

Our Abpromise guarantee covers the use of ab57466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionPutative neuronal cell surface protein involved in cell-cell-interactions.
    • Tissue specificityExpressed at highest levels in heart. Expressed at lower levels in liver, skeletal muscle and pancreas and at very low levels in brain.
    • Involvement in diseaseDefects in NLGN4X may be the cause of susceptibility to autism X-linked type 2 (AUTSX2) [MIM:300495]. AUTSX2 is a pervasive developmental disorder (PDD), prototypically characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age.
      Defects in NLGN4X may be the cause of susceptibility to X-linked Asperger syndrome 2 (ASPGX2) [MIM:300497]. ASPGX2 is considered to be a form of childhood autism.
    • Sequence similaritiesBelongs to the type-B carboxylesterase/lipase family.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • ASPGX2 antibody
      • AUTSX2 antibody
      • HLNX antibody
      • HNL4X antibody
      • HNLX antibody
      • KIAA1260 antibody
      • neuroligin 4, X-linked antibody
      • Neuroligin X antibody
      • Neuroligin-4 antibody
      • NL4 antibody
      • NLGN antibody
      • NLGN4 antibody
      • NLGN4X antibody
      • NLGNX_HUMAN antibody
      • OTTHUMP00000022863 antibody
      • OTTHUMP00000022864 antibody
      • OTTHUMP00000022865 antibody
      • X-linked antibody
      see all

    Anti-NLGN4X antibody images

    • Western blot against tagged recombinant protein immunogen using ab57466 Neuroligin 4 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    References for Anti-NLGN4X antibody (ab57466)

    ab57466 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57466.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"