Overview

  • Product nameAnti-NLGN4X antibody
    See all NLGN4X primary antibodies
  • Description
    Rabbit polyclonal to NLGN4X
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Chimpanzee, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 505-554 (PTELFSCNFS KNDVMLSAVV MTYWTNFAKT GDPNQPVPQD TKFIHTKPNR) of Human Neuroligin 4 (NP_065793)

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab81246 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 92 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionPutative neuronal cell surface protein involved in cell-cell-interactions.
  • Tissue specificityExpressed at highest levels in heart. Expressed at lower levels in liver, skeletal muscle and pancreas and at very low levels in brain.
  • Involvement in diseaseDefects in NLGN4X may be the cause of susceptibility to autism X-linked type 2 (AUTSX2) [MIM:300495]. AUTSX2 is a pervasive developmental disorder (PDD), prototypically characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age.
    Defects in NLGN4X may be the cause of susceptibility to X-linked Asperger syndrome 2 (ASPGX2) [MIM:300497]. ASPGX2 is considered to be a form of childhood autism.
  • Sequence similaritiesBelongs to the type-B carboxylesterase/lipase family.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ASPGX2 antibody
    • AUTSX2 antibody
    • HLNX antibody
    • HNL4X antibody
    • HNLX antibody
    • KIAA1260 antibody
    • neuroligin 4, X-linked antibody
    • Neuroligin X antibody
    • Neuroligin-4 antibody
    • NL4 antibody
    • NLGN antibody
    • NLGN4 antibody
    • NLGN4X antibody
    • NLGNX_HUMAN antibody
    • OTTHUMP00000022863 antibody
    • OTTHUMP00000022864 antibody
    • OTTHUMP00000022865 antibody
    • X-linked antibody
    see all

Anti-NLGN4X antibody images

  • Anti-NLGN4X antibody (ab81246) at 1 µg/ml + HeLa cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 92 kDa
    Observed band size : 80 kDa (why is the actual band size different from the predicted?)

References for Anti-NLGN4X antibody (ab81246)

ab81246 has not yet been referenced specifically in any publications.

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