Overview

  • Product name
  • Description
    Rabbit polyclonal to NLRC3
  • Specificity
    At least four isoforms of NLRC3 are known to exist; this antibody will recognize all of them. ab105339 is predicted to not cross-react with other NLRC family members.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A synthetic peptide (18 amino acids) from near the center of Human NLRC3 (EAW85351).

  • Positive control
    • 3T3 cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -20°C or -80°C.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab105339 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 115 kDa.

Target

  • Function
    May modulate T-cell activation. Decreases the transcription of genes that are normally up-regulated after T-cell stimulation. Delays degradation of NFKBIA/IKBA.
  • Tissue specificity
    Detected in peripheral blood mononuclear cells.
  • Sequence similarities
    Belongs to the NLRP family.
    Contains 16 LRR (leucine-rich) repeats.
    Contains 1 NACHT domain.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • CARD15-like antibody
    • CARD15-like protein antibody
    • Caterpiller 16.2 antibody
    • Caterpiller protein 16.2 antibody
    • CLR16.2 antibody
    • FLJ00348 antibody
    • NLR family CARD domain containing 3 antibody
    • Nlrc3 antibody
    • NLRC3_HUMAN antibody
    • NOD-like receptor C3 antibody
    • NOD3 antibody
    • NOD3 protein antibody
    • Nucleotide-binding oligomerization domain protein 3 antibody
    • Nucleotide-binding oligomerization domain protein 3 caterpiller 16.2 antibody
    • nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 3 antibody
    • Protein NLRC3 antibody
    see all

Images

  • Lane 1 : Anti-NLRC3 antibody (ab105339) at 1 µg/ml
    Lane 2 : Anti-NLRC3 antibody (ab105339) at 2 µg/ml

    Lane 1 : 3T3 cell lysate
    Lane 2 : 3T3 cell lysate

    Lysates/proteins at 15 µg per lane.

    Secondary
    Anti-rabbit secondary antibody

    Predicted band size : 115 kDa

References

ab105339 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab105339.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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