Overview

  • Product nameAnti-NLRC5 antibody
    See all NLRC5 primary antibodies
  • Description
    Rabbit polyclonal to NLRC5
  • Specificityab105411 is predicted to not cross react with other NLRP family members.
  • Tested applicationsSuitable for: ICC/IF, WB, ICCmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    An 18 amino acid peptide near the amino terminus of Human NLRC5 (NP_115582).

  • Positive control
    • EL4 cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab105411 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 205 kDa.Can be blocked with NLRC5 peptide (ab196047).
ICC Use a concentration of 10 µg/ml.

Target

  • FunctionProbable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms.
  • Tissue specificityExpressed in spleen, thymus, lung, brain, tonsil, heart and prostate.
  • Sequence similaritiesBelongs to the NLRP family.
    Contains 26 LRR (leucine-rich) repeats.
    Contains 1 NACHT domain.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Caterpiller protein 16.1 antibody
    • CLR16.1 antibody
    • FLJ21709 antibody
    • FLJ39711 antibody
    • NLR family, CARD domain containing 5 antibody
    • NLR family, CARD-containing 5 antibody
    • NLR family, caspase recruitment domain-containing 5 antibody
    • NLRC5 antibody
    • NLRC5_HUMAN antibody
    • NOD-like receptor C5 antibody
    • NOD27 antibody
    • NOD4 antibody
    • Nucleotide-binding oligomerization domain protein 27 antibody
    • Nucleotide-binding oligomerization domain protein 4 antibody
    • nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 5 antibody
    • nucleotide-binding oligomerization domains 27 antibody
    • OTTHUMP00000164675 antibody
    • Protein Caterpiller 16.1 antibody
    • Protein NLRC5 antibody
    see all

Anti-NLRC5 antibody images

  • Anti-NLRC5 antibody (ab105411) at 1 µg/ml + EL4 cell lysate

    Predicted band size : 205 kDa
  • Immunocytochemistry of NLRC5 in HeLa cells with ab105411 antibody at 10 µg/ml.
  • Immunofluorescence of NOD4 in Hela cells using ab105411 at 20 ug/ml.

References for Anti-NLRC5 antibody (ab105411)

This product has been referenced in:
  • Garcia PV  et al. Increased toll-like receptors and p53 levels regulate apoptosis and angiogenesis in non-muscle invasive bladder cancer: mechanism of action of P-MAPA biological response modifier. BMC Cancer 16:422 (2016). WB . Read more (PubMed: 27389279) »

See 1 Publication for this product

Product Wall

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As a positive control, we recommend using our EL4 lysate ab7183.

Our blocking peptide for this antibody has been made available as ab196047.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"