The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 149 kDa.
Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms.
Expressed in spleen, thymus, lung, brain, tonsil, heart and prostate.
Belongs to the NLRP family. Contains 26 LRR (leucine-rich) repeats. Contains 1 NACHT domain.