Overview

  • Product name
  • Description
    Rabbit polyclonal to NLRP10
  • Specificity
    At least two isoforms of NLRP10 are known to exist; this antibody will recognize both. The antibody is predicted to not cross-react with other NLRP family members.
  • Tested applications
    Suitable for: IHC-P, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A 14 amino acid peptide from near the N terminus of Human NLRP10 (NP_789791).

  • Positive control
    • Human brain tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab105407 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 75 kDa.

Target

  • Function
    Inhibits CASP1/caspase-1-dependent IL1B secretion and PYCARD-mediated apoptosis, but not that induced by FAS or BID.
  • Tissue specificity
    Widely expressed with highest levels in heart, brain and skeletal muscle.
  • Sequence similarities
    Belongs to the NLRP family.
    Contains 1 DAPIN domain.
    Contains 1 NACHT domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • CLR11.1 antibody
    • NACHT, leucine rich repeat and PYD containing 10 antibody
    • NACHT, LRR and PYD domains containing protein 10 antibody
    • NACHT, LRR and PYD domains-containing protein 10 antibody
    • NAL10_HUMAN antibody
    • NALP10 antibody
    • NLR family, pyrin domain containing 10 antibody
    • Nlrp10 antibody
    • NOD8 antibody
    • Nucleotide-binding oligomerization domain protein 8 antibody
    • Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10 antibody
    • PAN5 antibody
    • PYNOD antibody
    see all

Images

  • Immunofluorescence of NLRP10 in Human brain tissue with ab105407 at 20 ug/mL.

  • Immunohistochemistry of Human brain tissue with ab105407 at 10 μg/mL.

  • Anti-NLRP10 antibody (ab105407) at 1 µg/ml + Human brain tissue lysate at 15 µg

    Predicted band size : 75 kDa

References

ab105407 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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