For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
Shipped at 4°C. Store at +4°C.
Preservative: 0.02% Sodium Azide
Concentration information loading...
Immunogen affinity purified
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 10 µg/ml.
||Use a concentration of 20 µg/ml.
||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 112 kDa.
Inhibits CASP1/caspase-1-dependent IL1B secretion.
Expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. Not detected in skeletal muscle.
Involvement in disease
Defects in NLRP7 are the cause of hydatidiform mole (HYDM) [MIM:231090]. HYDM is an abnormal human pregnancy with no embryo and cystic degeneration of placental villi.
Belongs to the NLRP family.
Contains 1 DAPIN domain.
Contains 9 LRR (leucine-rich) repeats.
Contains 1 NACHT domain.
Information by UniProt
- CLR19.4 antibody
- FLJ94610 antibody
- HYDM antibody
Anti-NLRP7 antibody images
References for Anti-NLRP7 antibody (ab105405)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"