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Rabbit polyclonal to NLRP7
Synthetic peptide conjugated to KLH, corresponding to a region from the N-terminus of Human NLRP7.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 111 kDa.
||Use at an assay dependent concentration.
||Use a concentration of 5 µg/ml.
Inhibits CASP1/caspase-1-dependent IL1B secretion.
Expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. Not detected in skeletal muscle.
Involvement in disease
Defects in NLRP7 are the cause of hydatidiform mole (HYDM) [MIM:231090]. HYDM is an abnormal human pregnancy with no embryo and cystic degeneration of placental villi.
Belongs to the NLRP family.
Contains 1 DAPIN domain.
Contains 9 LRR (leucine-rich) repeats.
Contains 1 NACHT domain.
Information by UniProt
- CLR19.4 antibody
- FLJ94610 antibody
- HYDM antibody
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"