Overview

  • Product nameAnti-NM23A antibody
    See all NM23A primary antibodies
  • Description
    Chicken polyclonal to NM23A
  • Specificityab37680 recognises nm23a, expressed in lung carcinoma cell lines but not in normal lung tissues.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) (Human) NM23A

Properties

Applications

Our Abpromise guarantee covers the use of ab37680 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Predicted molecular weight: 17 kDa.

Target

  • FunctionMajor role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination.
  • Tissue specificityIsoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. Isoform 3 is ubiquitously expressed.
  • Sequence similaritiesBelongs to the NDK family.
  • Cellular localizationCytoplasm. Nucleus. Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA.
  • Information by UniProt
  • Database links
  • Alternative names
    • AWD antibody
    • AWD, drosophila, homolog of antibody
    • GAAD antibody
    • Granzyme A activated DNase antibody
    • Granzyme A-activated DNase antibody
    • GZMA activated DNase antibody
    • Metastasis inhibition factor NM23 antibody
    • NB antibody
    • NBS antibody
    • NDK A antibody
    • NDKA antibody
    • NDKA_HUMAN antibody
    • NDP kinase A antibody
    • NDPK-A antibody
    • NDPKA antibody
    • NM23 antibody
    • NM23 long variant, included antibody
    • nm23-H1 antibody
    • NM23-M1 antibody
    • NM23H1B, included antibody
    • NME/NM23 nucleoside diphosphate kinase 1 antibody
    • Nme1 antibody
    • NME1-NME2 spliced read-through transcript, included antibody
    • Non-metastatic cells 1, protein (NM23A) expressed in antibody
    • Nonmetastatic cells 1, protein expressed in antibody
    • Nonmetastatic protein 23 antibody
    • Nonmetastatic protein 23, homolog 1 antibody
    • Nucleoside diphosphate kinase A antibody
    • Tumor metastatic process-associated protein antibody
    see all

References for Anti-NM23A antibody (ab37680)

ab37680 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Human Cell lysate - other (SW1353 chondrosarcoma)
Loading amount 15 µg
Specification SW1353 chondrosarcoma
Gel Running Conditions Reduced Denaturing (15% SDS-PAGE)
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 22°C
Username

Dr. Ursula Rodgers

Verified customer

Submitted Jun 17 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"