Overview

  • Product name
    Anti-NM23A antibody [EPR10146]
    See all NM23A primary antibodies
  • Description
    Rabbit monoclonal [EPR10146] to NM23A
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF or IP
  • Species reactivity
    Reacts with: Human
    Does not react with: Mouse, Rat
  • Immunogen

    Recombinant fragment within Human NM23A. The exact sequence is proprietary.
    Database link: P15531

  • Positive control
    • Hela, MCF7 and Jurkat cell lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.2
    Preservative: 0.01% Sodium azide
    Constituents: 50% Glycerol, 0.05% BSA, 49% PBS
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR10146
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab171935 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 17 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF or IP.
  • Target

    • Function
      Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination.
    • Tissue specificity
      Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. Isoform 3 is ubiquitously expressed.
    • Sequence similarities
      Belongs to the NDK family.
    • Cellular localization
      Cytoplasm. Nucleus. Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA.
    • Information by UniProt
    • Database links
    • Alternative names
      • AWD antibody
      • AWD, drosophila, homolog of antibody
      • GAAD antibody
      • Granzyme A activated DNase antibody
      • Granzyme A-activated DNase antibody
      • GZMA activated DNase antibody
      • Metastasis inhibition factor NM23 antibody
      • NB antibody
      • NBS antibody
      • NDK A antibody
      • NDKA antibody
      • NDKA_HUMAN antibody
      • NDP kinase A antibody
      • NDPK-A antibody
      • NDPKA antibody
      • NM23 antibody
      • NM23 long variant, included antibody
      • nm23-H1 antibody
      • NM23-M1 antibody
      • NM23H1B, included antibody
      • NME/NM23 nucleoside diphosphate kinase 1 antibody
      • Nme1 antibody
      • NME1-NME2 spliced read-through transcript, included antibody
      • Non-metastatic cells 1, protein (NM23A) expressed in antibody
      • Nonmetastatic cells 1, protein expressed in antibody
      • Nonmetastatic protein 23 antibody
      • Nonmetastatic protein 23, homolog 1 antibody
      • Nucleoside diphosphate kinase A antibody
      • Tumor metastatic process-associated protein antibody
      see all

    Images

    • All lanes : Anti-NM23A antibody [EPR10146] (ab171935) at 1/1000 dilution

      Lane 1 : HeLa cell line lysate
      Lane 2 : MCF7 cell line lysate
      Lane 3 : Jurkat cell line lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat ant-rabbit HRP conjugated antibody at 1/500 dilution

      Developed using the ECL technique.

      Predicted band size: 17 kDa

    References

    This product has been referenced in:
    • Qu S  et al. Protein expression of nucleophosmin, annexin A3 and nm23-H1 correlates with human nasopharyngeal carcinoma radioresistance in vivo. Oncol Lett 12:615-620 (2016). IHC-P ; Human . Read more (PubMed: 27347189) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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