Anti-NMDAR1 antibody [0.T.190] (ab32915)


  • Product nameAnti-NMDAR1 antibody [0.T.190]
    See all NMDAR1 primary antibodies
  • Description
    Mouse monoclonal [0.T.190] to NMDAR1
  • SpecificityThis antibody is specific to NMDAR1. The epitope maps to a region common to all NMDAR1 isoforms and so should crossreact with all NMDAR1 isoforms.
  • Tested applicationsSuitable for: WB, IP, ICC/IFmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse, Human
  • Immunogen

    His tag fusion protein, corresponding to amino acids 834-938 of Rat NMDAR1.

  • EpitopeRegion 834-864 of NMDAR1.
  • Positive control
    • ICC/IF: QT6 cells and cultured rat neurons. WB, IP: rat brain microsomal protein preparation.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPreservative: 0.035% Sodium Azide.
    Constituents: 30% Glycerol, 0.105M Sodium chloride, 0.07M Tris glycine.
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number0.T.190
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab32915 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 106 kDa. Detects NMDAR1 from 20µg of rat brain microsomal protein preparation.
IP Use at an assay dependent dilution. 4µg immunoprecipitated NMDAR1 from 500µg of rat brain microsomal protein preparation.
ICC/IF Use at an assay dependent dilution. Cells fixed with 4% paraformaldehyde/4% sucrose in PBS.


  • FunctionNMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.
  • Sequence similaritiesBelongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
  • Post-translational
    NMDA is probably regulated by C-terminal phosphorylation of an isoform of NR1 by PKC. Dephosphorylated on Ser-897 probably by protein phosphatase 2A (PPP2CB). Its phosphorylated state is influenced by the formation of the NMDAR-PPP2CB complex and the NMDAR channel activity.
  • Cellular localizationCell membrane. Cell junction > synapse > postsynaptic cell membrane. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Enriched in post-synaptic plasma membrane and post-synaptic densities.
  • Information by UniProt
  • Database links
  • Alternative names
    • GluN1 antibody
    • Glutamate [NMDA] receptor subunit zeta-1 antibody
    • Glutamate receptor ionotropic N methyl D aspartate 1 antibody
    • Glutamate receptor ionotropic, N-methyl-D aspartate, subunit 1 antibody
    • glutamate receptor ionotropic, NMDA 1 antibody
    • Grin1 antibody
    • MRD8 antibody
    • N methyl D aspartate receptor antibody
    • N methyl D aspartate receptor channel subunit zeta 1 antibody
    • N methyl D aspartate receptor subunit NR1 antibody
    • N-methyl-D-aspartate receptor subunit NR1 antibody
    • NMD-R1 antibody
    • NMDA 1 antibody
    • NMDA R1 antibody
    • NMDA receptor 1 antibody
    • NMDA1 antibody
    • NMDAR antibody
    • NMDZ1_HUMAN antibody
    • NR1 antibody
    see all

References for Anti-NMDAR1 antibody [0.T.190] (ab32915)

ab32915 has not yet been referenced specifically in any publications.

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